Hormonal Sleep

Hormonal Sleep Disruption in Women: What It Is, How It Fragments Sleep, and How to Recognize It

Overview: Estrogen, progesterone, and their downstream metabolites regulate multiple pathways that govern sleep — from the brain’s inhibitory tone to body temperature to the neurotransmitters that set the sleep-wake cycle. As these hormones’ function is disrupted during perimenopause and menopause, each pathway is affected in a specific way: Progesterone is converted to allopregnanolone, a neurosteroid […]

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Hormonal Sleep Disruption in Men: How Declining Testosterone Function, Growth Hormone, and DHEA Fragment Sleep After 40

Testosterone, growth hormone, and DHEA all decline as men age — starting as early as the late 20s and accelerating after 40. These hormonal changes don’t reduce sex drive and muscle mass alone; they directly alter the brain’s ability to produce and maintain deep sleep. Declining testosterone function involves three concurrent changes: falling production from

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