Personalized longevity roadmap for 2026 labs & sleep
Longevity work becomes powerful when last night’s sleep, today’s meals, and your next blood draw are all pulling in the same direction.
2026 is your opportunity to get there.
This launchpad brings together the Vault’s most practical resources—across sleep, hormones, LDL cholesterol, inflammation, kidney health, and brain protection—organized by focus area so you can find what resonates, protect brain health, and lower long-term risk with deliberate, targeted steps.
Let’s get started.

6 high-impact pieces to guide your 2026 sleep, cardiometabolic health and labs for longevity optimization
These pieces give you a high-level view of how sleep, hormones, kidneys, and LDL intersect with brain health & long-term risk.
If you only revisit a handful of articles to orient your 2026 focus, start with one or two from this group.
- Does “deep sleep” clear Alzheimer’s proteins?
- Melatonin as a Longevity Molecule? Safety Data, Metabolic Risks, and Antioxidant Promise
- Are My Hormones Affecting My Sleep? An Overlooked Reason Hormone Therapy Falls Short
- 3 A.M. Wake-Ups: It’s Not Just Stress
- Kidney stones: Is avoiding spinach enough?
- “My LDL-C is 186—I eat whole foods & exercise: what else is left to do?”
Select personalizable tools & frameworks to lower inflammation, cholesterol, and improve sleep for better aging outcomes
These are the pieces to come back to when you’re ready to adjust something concrete—nutritional pitfalls that undermine longevity, lab follow-up, or how you use melatonin.
Pick one tool that matches your current friction point, run it, then come back for the next:
- The Vault Food-Inflammation Audit: A 6-Part Protocol for Stubborn Inflammation & Lipid Markers
- 6-Part Framework To Detect Early Aging from Routine Labs & Reverse Course (SPIRAL)
- Why Melatonin Often Don’t Deliver (& 5 Safe Adjustments for Better Sleep)
- Elevated White Blood Cell Count Within Normal Range Consistently Linked to Higher Mortality in Large Studies (& What You Can Do Today)
Explore by focus area: brain health, staying asleep, nutrition & daily longevity choices
Use this section to jump straight to the collection of articles that matches the aspect of longevity you’re working on now—sleep, hormone-related sleep, lab-based prevention, or day-to-day choices that reduce LDL cholesterol, inflammation, and brain health risk.
What can I change in how I sleep now to better protect my brain and long-term aging?
Routine labs for heart, brain & long-term aging
How can I use my usual blood tests to adjust my plan and lower future heart and brain risk?
Staying asleep & 3 a.m. wake-ups
Why am I waking up in the middle of the night, and what can I do about it?
What steps can I take if I suspect hormones are disrupting my sleep in midlife?
What should I change in daily choices, nutrition, and supplements to improve cholesterol levels, reduce inflammation, and lower kidney stone risk?
This page features a selection of Longevity Resources:
You can always browse the full Longevity Vault collection here.



